about

2012

2015

2021

2015

2018

2021

Kangli Wang

Contact

Education

Projects

I am currently a postdoc fellow at UCSanDiego. My research interests are bioinformatics, epigenetics, and genomics. We focus on decipher the origin of neuron transformation after gene knockdown now.

Email：dzq0123456789@live.com

Github：https://github.com/wkl1990

Sichuan Agriculture University

Biological Science

Wenzhou Medical University

Biology

Central South University

Genetics

Q-RRBS

Q-RRBS is a DNAm sequencing method, which could eliminate PCR-induced artifacts and detect methylome profiling accurately, especially powerful for single cell. The paper has been published on Epigenetics journal.

CNV-lncRNAs

CNV-lncRNAs investigated lncRNAs within 10 SCZ risk–associated CNV deletion regions and examined their potential contribution to SCZ risk. WGCNA analysis on transcriptome of brain tissue identified one neuronal function–related coexpression module contained a hub lncRNA called DGCR5 within the 22q11.2 CNV region. The paper has been published on Science Translational Medicine journal.

GCPs

GCPs project aims to investigate how DNAm and gene expression are coordinated across different human tissues and developmental stages, as well as the biological significance of such correlations. The majority of correlated gene-CpG pairs were tissue- or development-specific and the correlation direction can be opposite in different tissues and ages. The paper has been published on under Epigenetics journal.